|
KMID : 0374920050260010075
|
|
Inje Medical Journal
2005 Volume.26 No. 1 p.75 ~ p.84
|
|
|
Hemodynamic Effects of Remifentanil Electroconvulsive Therapy
|
|
Cheong Soon-Ho
Lee Kun-Moo
Lim Se-Hun
Lee Jeong-Han
Choe Young-Kyun
Kim Young-Jae
Shin Chee-Mahn
Lee Sang-Eun
|
|
|
Abstract
|
|
|
Objective: Electroconvulsive therapy (ECT) is often associated with transient hypertension and tachycardia. Acute hemodynamic change may produce serious complications. Remifentanil is a potent ultra short acting opioid and has been found to reduce blood pressure and heart rate. The goal of this study was to evaluate effects of remifentanil on seizure duration, recovery parameters and hemodynamic changes during ECT.
Methods: Ten ASA Ⅰ, Ⅱ patients enrolled in this prospective, randomized trial, each receiving more than four electroconvulsive therapy. Patients were randomized to receive placebo, group P (propofol 1mg/kg+0.9% normal saline 1ml, n=10), and propofol with remifentanil, group R (propofol 1mg/kg+remifentanil 1ug/Kg n=10). Supplemental dose of propofol was given as required to achieve loss of consciousness. We recorded hemodynamic parameters, seizure duration, and recovery parameters.
Results: Seizure duration and recovery parameters were similar in group R and group P. Blood pressure and Hear rate after ECT were significantly lower in group R.
Conclusions: Remifentanil(1ug/kg) attenuated the acute hemodynamic response to ECT under propofol anesthesia without adversely affecting the duration of seizure activity and recovery profile. Adjunctive use of remifentanil may be good alternative regimens for ECT.
|
|
|
KEYWORD
|
|
|
ECT, Propofol, Remifentanil
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|